2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Phosphodiesterase (PDE)
  5. PDE4 Isoform
  6. PDE4 Activator

PDE4 Activator

PDE4 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-128358
    MR-L2
    		Activator 99.23%
    MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM.